Ron Agatep; Peter Ainsworth; Mohammad R Akbari; Melyssa Aronson; Gary Bader; Raveen Basran; Andre Blavier; Andrea Blumenthal; Ian Bosdet; Kym Boycott; Michael Brudno; Kathleen Buckley; Jodi Campbell; Philippe M Campeau; Melanie Care; Nancy Carson; Ronald Carter; George Charames; David Chitayat; George Chong; Edmond Chouinard; Kathy Chun; Kenneth J Craddock; Rod Docking; Andrea Eisen; Hanna Faghfoury; Sandra Farrell; Harriet Feilotter; Bridget Fernandez; Marc Fiume; Cynthia Forster-Gibson; Jan Friedman; William Foulkes; Peter Goodhand; Jessica Gu; Robert Hegele; Spring Holter; Sheri Horsburgh; Lauren Hughes; Stacey Hume; Olga Jarinova; Franny Jewett; Anne Junker; Aly Karsan; Sam Khalouei; Joan Knoll; Elena Kolomeitz; Bartha Knoppers; Ryan Lamont; Matthew Lebo; Jordan Lerner-Ellis; Georges Maire; Christian Marshall; Elizabeth McCready; Grant Mitchell; Michael J Moorhouse; Chantal Morel; Tanya Nelson; Abdul Noor; Brian O’Connor; Darren O’Rielly; Francis Ouellette; Jillian Parboosingh; Hilary Racher; Peter Ray; Heidi Rehm; Christie Riddell; Jean-Baptiste Riviere; David S Rosenblatt; Guy Rouleau;  Andrea Ruchon; Peter Sabatini; Bekim Sadikovic; Kara Semotiuk; Stephen W Scherer; Cheryl Shuman; Josh Silver; Katherine Siminovitch; Lesley Solomon-Izsak; Jean-Francois Soucy; Marsha Speevak; James Stavropoulos; Lincoln Stein; Rhonda Tannenbaum; Sherryl Taylor; Deborah Terespolsky; Robert Tomaszewski; Tracy Tucker; Richard F Wintle; Beatrix Wong; Nora Wong; Marina Wang; John S Waye; Shana White; Michael O Woods; Philip Wyatt; Sean Young; Kathleen-Rose Zakoor

The Executive Committee is charged with overall supervision of the project, and is responsible for budget, scheduling and workgroup coordination.

• Jordan Lerner-Ellis, PhD, FACMG – PI
  Mount Sinai Hospital, University of Toronto
• Matthew Lebo, PhD, FACMG – PI
  Partners Healthcare Personalized Medicine
• Brian O’Connor, PhD
  Ontario Institute of Cancer Research
• Gary Bader, PhD
  University of Toronto
• Katherine Siminiovitch, MD, FRCPC, FACP
  University of Health Network, Mount Sinai Hospital
• Lincoln Stein, MD, PhD
  Ontario Institute of Cancer Research
• Kathleen-Rose Zakoor
  Mount Sinai Hospital

The Bioinformatics and IT Workgroup is responsible for sourcing and developing software and other tools to interpret genetic variation; extracting data from participating labs; and making all project information available to the community at large. This workgroup will be developing, refining, and disseminating the novel variants assessment and phenotype cataloguing tools. They will also be responsible for creating the bioinformatic processes for extracting variant level knowledge data from the various external databases, standardizing the data, and importing it into the unified database.  The Bioinformatics and IT Workgroup will also develop and maintain the website with direct input from the other two working groups. 

• Shana White, MS, CGC
  Partners Healthcare Personalized Medicine
• Kathleen-Rose Zakoor
  Mount Sinai Hospital
• Andre Blavier, MD, MS
  Interactive Biosoftware
• Brian O’Connor, PhD
  Ontario Institute of Cancer Research
• Christian Marshall, PhD
  McLaughlin Centre, University of Toronto
• Francis Ouellette
  Ontario Institute for Cancer Research
• Gary Bader, PhD
  University of Toronto
• Lincoln Stein, MD, PhD
  Ontario Institute of Cancer Research
• Matthew Lebo, PhD, FACMG – PI
  Partners Healthcare Personalized Medicine

The Data Collection and Standards Workgroup is responsible for defining and monitoring the operational goals of the project, including the scope of data collection, data sources and requirements for shared resources. This group is made up of representatives from each clinical or research laboratory contributing data to the project.  This workgroup will be responsible for collecting and synthesizing data from the various stakeholders, communicating these analyses and equivalencies to the Bioinformatics workgroup, and producing the SOPs, guidelines, and policies surrounding the use of the novel variant assessment tool, phenotype cataloguing system, and unified database.

• Aly Karsan, MD
  British Columbia Cancer Agency
• Andrea Ruchon, MD, PhD, FCCMG
  McMaster University Health Sciences Centre
• Bekim Sadikovic, PhD, DABMG, FACMG
  McMaster University Health Sciences Centre
• Bridget Fernandez, MD, FRCPC, FCCMG
  Memorial University of Newfoundland
• Christian Marshall, PhD
  SickKids Hospital
• Christie Riddell, PhD
  Dalhousie University
• Elena Kolomeitz, PhD, FCCMG
  Mount Sinai Hospital
• Elizabeth McCready, PhD, MSc, FCCMG
  McMaster’s University, Hamilton Health Sciences
• Elizabeth Spriggs, PhD, FCCMG
  University of Manitoba
• Franny Jewett
  Impact Genetics Inc
• George Charames, PhD
  Mount Sinai Hospital
• George Chong, PhD
  Jewish General Hospital
• Georges Maire, MSc, PhD
  Mount Sinai Hospital
• Harriet Feilotter, PhD, FCCMG
  Queen’s University
• John Waye, PhD, ABMG, FACMG
  McMaster’s University, Hamilton Health Sciences
• Peter Ray, PhD
  SickKids Hospital
• Philippe Campeau, MD
  Sainte-Justine University Hospital Research Center
• Heidi Rehm, PhD, FACMG
  Brigham and Women’s Hospital and Harvard Medical School, PCPGM
• James Stavropoulos, PhD, FCCMG
  SickKids Hospital
• Jillian Parboosingh, BSc, MSc, PhD
  Alberta Children’s Hospital
• Jordan Lerner-Ellis, PhD, FACMG – PI
  Mount Sinai Hospital
• Kathleen-Rose Zakoor
  Mount Sinai Hospital
• Kathy Chun, PhD, FCCMG, FACMG
  North York General Hospital
• Ken Craddock, MD, FCCMG
  University Health Network
• Marsha Speevak, PhD, FCCMG
  Trillium Health Partners – Credit Valley Site
• Matthew Lebo, PhD, FACMG – PI
  Partners Healthcare Center for Personalized Genetic Medicine
• Michael O. Woods, PhD
  Memorial University
• Mohammad R Akbari, PhD
  Research Molecular Genetic Lab, Women’s College Hospital
• Nancy Carson, PhD, FCCMG
  CHEO
• Peter Ainsworth, MBChB, PhD, FRCPC
  Western University
• Raveen Basran, ABMG
  SickKids Hospital
• Richard Wintle
  The Centre for Applied Genomics
• Robert Hegele, MD, FRCPC, FACP
  Robarts Research Institute, Western University
• Rod Docking, MSc
  British Columbia Cancer Agency
• Ron Agatep, PhD, FCCMG
  McGill University Health Complex, McGill University
• Sam Khalouei, PhD
  Mount Sinai Hospital
• Sandra Farrell
  Credit Valley Hospital, Trillium Health Centre
• Sean Young, PhD, DABMG, FACMG, FCCMG
  British Columbia Cancer Agency, University of British Columbia
• Stacey Hume, PhD, FCCMG
  Alberta Health Services, University of Alberta
• Tanya N. Nelson, PhD, FCCMG
  BC Children’s and Women’s Hospitals, University of British Columbia

The Outreach and Patient Advocacy Workgroup is responsible for creating awareness of and interest in the long-term benefits of the project, by developing relationships and interactive communications vehicles that will allow the project team to keep all stakeholders up-to-date on our progress, as well as to stay abreast of developments affecting end-users, including patients and groups advocating for the identification and management of both rare and common diseases.

• Andrea Blumenthal, MD, FRCPC, FCCMG
  Lakeridge Health
• Andrea Eisen, MD, FRCPC
  Sunnybrook Health Sciences Centre
• Chantal Morel, MD, FRCPC, FCCMG
  UHN MSH Fred A Litwin Family Centre in Genetic Medicine
  
• Cheryl Shuman, MS, CGC
  Hospital for Sick Children
• Cynthia Forster-Gibson
  Peterborough Regional Health Centre
• David Chitayat, MD, FABMG, FACMG, FCCMG, FRCPC
  Mount Sinai Hospital
• David S. Rosenblatt, MD
  McGill University
  
• Deborah Terespolsky, MBBCh, FRCPC, FCCMG
  Credit Valley Hospital, Trillium Health Centre
• Edmond Chouinard, MD, FRCPC
  Grand River Regional Cancer Centre
• Hanna Faghfoury, MDCM
  University Health Network
  
• Joan Knoll, PhD, DABMG, FCCMG
  Western University
• Jodi Campbell, MSc, CGC, CCGC
  The Credit Valley Hospital
  
• Josh Silver, MSc, CGC, CCGC
  University Health Network, Mount Sinai Hospital
• Kara Semotiuk, MS, CCGC
  Familial Gastrointestinal Cancer Registry, Mount Sinai Hospital
• Katherine Siminiovitch, MD, FRCPC, FACP
  University of Health Network, Mount Sinai Hospital
• Kathleen Buckley, MSc, (C) CGC
  Grand River Regional Cancer Centre
• Kathleen-Rose Zakoor
  Mount Sinai Hospital
• Lauren Hughes, MS, CCGC
  Orillia Soldier’s Memorial Hospital
• Lesley Solomon-Izsak
  Mackenzie Health Richmond Hill Hospital
  
• Melanie Care, CGC
  University Health Network, Mount Sinai Hospital
• Melyssa Aronson, CGC
  Familial Gastrointestinal Cancer Registry, Mount Sinai Hospital
• Nora Wong, CGC
  Jewish General Hospital
• Philip Wyatt, MD, PhD
  Orillia Soldier’s Memorial Hospital, Mackenzie Health Richmond Hill Hospital
  
• Rhonda Tannenbaum
  Ontario Genomics Institute
• Sheri Horsburgh, MSc
  University Health Network, Mount Sinai Hospital
• Spring Holter, MS, CCGC
  Familial Gastrointestinal Cancer Registry, Mount Sinai Hospital
• Stephen Scherer, PhD, DSc, FRSC
  McLaughlin Centre, University of Toronto
• William Foulkes, MD, PhD
  McGill University Health Network, Jewish General Hospital, Montreal General Hospital

Organizations, Projects, and Consortia with Related Missions

1000 Genomes Project

Canadian College of Medical Geneticists

Clinical Genetics Society

Clinical Sequencing Exploratory Research Consortium

ClinVar

DECIPHER

Electronic Medical Records and Genomics (eMERGE) Network

Exome Sequencing Project (ESP)

GeneReviews

Human Variome Project

International Collaboration for Clinical Genomics

International Rare Diseases Research Consortium (IRDiRC)

Leiden Open Variation Database (LOVD)

National Center for Biotechnology Information

Online Mendelian Inheritance in Man (OMIM)

Pharmacogenetics Knowledge Base (PharmGKB)

Pharmacogenetics Research Network

Sharing Clinical Reports Project (SCRP)

Professional Societies

American College of Medical Genetics

American Society of Human Genetics

Association for Molecular Pathology

College of American Pathologists

Government Agencies

Centers for Disease Control and Prevention

Food and Drug Administration

National Human Genome Research Institute

National Institute of Child Health and Human Development

National Institutes of Health

Patient Advocacy

Free the Data 

Genetic Alliance

Global Rare Diseases Registry

Unique